Berkeley is a town and parish in Gloucestershire, England. It depends on the Vale of Berkeley in between the east financial institution of the River Severn and also the M5 motorway, within the Stroud management area. The community is kept in mind for Berkeley Castle, where the sent to prison Edward II was killed, in addition to the birth place of the medical professional Edward Jenner, pioneer of the smallpox injection, the world's first injection. The church includes the town of Berkeley Heath, which runs along the A38 Bristol to Gloucester road as well as the adjacent B4066 towards Berkeley. An electoral ward in the same name exists. This ward extends from Berkeley in the south to Hinton in the north. The total ward population taken at the 2011 census was 4,181.