Berkeley is a town and also parish in Gloucestershire, England. It depends on the Vale of Berkeley in between the east bank of the River Severn and also the M5 motorway, within the Stroud management district. The community is noted for Berkeley Castle, where the imprisoned Edward II was killed, as well as the birth place of the doctor Edward Jenner, leader of the smallpox vaccine, the globe's very first vaccination. The parish includes the village of Berkeley Health, which leaves the A38 Bristol to Gloucester roadway as well as the nearby B4066 in the direction of Berkeley. A selecting ward in the very same name exists. This ward stretches from Berkeley in the south to Hinton in the north. The complete ward population taken at the 2011 census was 4,181.